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    Complete genome sequences of six Legionella pneumophila isolates from two collocated outbreaks of legionnaires' disease in 2005 and 2008 in Sarpsborg/Fredrikstad, Norway

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    1453326.pdf (148.0Kb)
    Date
    2016
    Author
    Dybwad, Marius
    Aarskaug, Tone
    Fykse, Else-Marie
    Madslien, Elisabeth Henie
    Blatny, Janet Martha
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    Abstract
    Here, we report the complete genome sequences of Legionella pneumophila isolates from two collocated outbreaks of Legionnaires’ disease in 2005 and 2008 in Sarpsborg/Fredrikstad, Norway. One clinical and two environmental isolates were sequenced from each outbreak. The genome of all six isolates consisted of a 3.36 Mb-chromosome, while the 2005 genomes featured an additional 68 kb-episome sharing high sequence similarity with the L. pneumophila Lens plasmid. All six genomes contained multiple mobile genetic elements including novel combinations of type-IVA secretion systems. A comparative genomics study will be launched to resolve the genetic relationship between the L. pneumophila isolates.
    URI
    http://hdl.handle.net/20.500.12242/610
    https://ffi-publikasjoner.archive.knowledgearc.net/handle/20.500.12242/610
    DOI
    10.1128/genomeA.01367-16
    Description
    Dybwad, Marius; Aarskaug, Tone; Fykse, Else-Marie; Madslien, Elisabeth Henie; Blatny, Janet Martha. Complete genome sequences of six Legionella pneumophila isolates from two collocated outbreaks of legionnaires' disease in 2005 and 2008 in Sarpsborg/Fredrikstad, Norway. Genome Announcements 2016 ;Volum 4.(6)
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