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dc.contributor.authorRøen, Bent Tore
dc.contributor.authorOpstad, Aase Mari
dc.contributor.authorHaavind, Anniken
dc.contributor.authorTønsager, Janne
dc.date.accessioned2014-01-02T12:19:53Z
dc.date.accessioned2016-03-08T14:47:46Z
dc.date.available2014-01-02T12:19:53Z
dc.date.available2016-03-08T14:47:46Z
dc.date.issued2013
dc.identifier.citationJournal of Analytical Toxicology 2013, 37(5):313-317en_GB
dc.identifier.urihttps://ffi-publikasjoner.archive.knowledgearc.net/handle/20.500.12242/29
dc.descriptionRøen, Bent Tore; Opstad, Aase Mari; Haavind, Anniken; Tønsager, Janne. Serial Ricinine Levels in Serum and Urine after Ricin Intoxication. Journal of Analytical Toxicology 2013 ;Volum 37.(5) s. 313-317en_GB
dc.description.abstractRicinine is an alkaloid present in the castor bean plant (Ricinus communis) that can be used as a biomarker for ricin poisoning. Serial ricinine levels are reported in the serum and urine of a patient suffering from intentional ricin intoxication. The patient was brought to the hospital 4 h after injection and oral intake of a castor bean extract, but died 38 h later, despite intensive medical care. Ricinine was isolated from the samples by solid-phase extraction and quantitatively determined by isotopic dilution liquid chromatography–mass spectrometry. The ricinine level in serum declined from 33 to 23 ng/mL between 10 and 29 h post-exposure. Three urine samples collected from 12 to 41 h after ricin intoxication showed ricinine concentrations in the range of 20–58 ng/mL. The creatinine corrected values (21–30 µg/g) indicated a concentration–time profile with a maximum ricinine level in urine between 12 and 29 h after exposure.en_GB
dc.language.isoenen_GB
dc.subjectRicin
dc.subjectForgiftning
dc.titleSerial Ricinine Levels in Serum and Urine after Ricin Intoxicationen_GB
dc.typeArticleen_GB
dc.date.updated2014-01-02T12:19:53Z
dc.identifier.cristinID1039203
dc.identifier.cristinID1039203
dc.identifier.doi10.1093/jat/bkt026
dc.source.issn0146-4760
dc.type.documentJournal article


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