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Two medical therapies very effective shortly after high levels of soman poisoning in rats, but only one with universal utility
(2013)
A treatment regimen consisting of HI-6, scopolamine, and physostigmine (termed the physostigmine regimen) has been based on the serendipitous discovery that it exerts powerful antidotal effects against high levels of soman ...
Supralethal poisoning by any of the classical nerve agents is effectively counteracted by procyclidine regimens in rats
(2015)
A treatment regimen consisting of HI-6, levetiracetam, and procyclidine (termed the triple regimen) has previously been shown to work as a universal therapy against soman poisoning in rats, since it has capacities to ...
Capacities of metabotropic glutamate modulators in counteracting soman-induced seizures in rats
(2013)
The mechanisms underlying insulin sensitivity and fat tissue distribution in chronic renal insufficiency remain unclear. Previous studies have shown the benefits of angiotensin II receptor blockers on moderately nourished ...
Development of neuropathology following soman poisoning and medical countermeasures
(2018)
Nerve agent-induced seizures can cause varying degrees of neuropathology depending on level of poisoning and duration of seizing. The intention of this review was to validate a novel approach for establishing effective ...