Browsing by Author "Enger, Siri"
Now showing items 1-7 of 7
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Behavioral side effects of prophylactic therapies against soman-induced seizures and lethality in rats
Myhrer, Trond; Enger, Siri; Aas, Pål (2014)Four medical therapies previously shown to exert varying degrees of protection against a convulsant dose of soman were assessed for potential behavioral side effects in a novelty test. In Experiment 1, HI-6 (1-[([4-(amin ... -
Capacities of metabotropic glutamate modulators in counteracting soman-induced seizures in rats
Myhrer, Trond; Mariussen, Espen; Enger, Siri; Aas, Pål (2013)The mechanisms underlying insulin sensitivity and fat tissue distribution in chronic renal insufficiency remain unclear. Previous studies have shown the benefits of angiotensin II receptor blockers on moderately nourished ... -
Evaluering av tre typer autoinjektor-regimer mot nervegassforgiftning
Aas, Pål; Enger, Siri; Myhrer, Trond (2011-12-15)Forsvaret er utstyrt med akuttmedisinske motmidler som har til formål å redusere skader på mennesker og å øke overlevelse etter nervegasseksponering. Dette er legemidler som skal benyttes både profylaktisk og i oppfølgende ... -
Multichannel open tubular enzyme reactor online coupled with mass spectrometry for detecting ricin
Brandtzaeg, Ole Kristian; Røen, Bent Tore; Enger, Siri; Lundanes, Elsa; Wilson, Steven Ray Haakon (2017)For counterterrorism purposes, a selective nano liquid chromatography–mass spectrometry (nanoLC-MS) platform was developed for detecting the highly lethal protein ricin from castor bean extract. Manual sample preparation ... -
The perirhinal cortex of rats: An intricate area for microinfusion of anticonvulsants against soman-induced seizures
Myhrer, Trond; Enger, Siri; Aas, Pål (2013)Microinfusion of anticonvulsants into the perirhinal cortex through 1 guide cannula in each hemisphere only invades a small area of this seizure controlling site in rats exposed to soman. The purpose of the present study ... -
Supralethal poisoning by any of the classical nerve agents is effectively counteracted by procyclidine regimens in rats
Myhrer, Trond; Mariussen, Espen; Enger, Siri; Aas, Pål (2015)A treatment regimen consisting of HI-6, levetiracetam, and procyclidine (termed the triple regimen) has previously been shown to work as a universal therapy against soman poisoning in rats, since it has capacities to ... -
Two medical therapies very effective shortly after high levels of soman poisoning in rats, but only one with universal utility
Myhrer, Trond; Enger, Siri; Mariussen, Espen; Aas, Pål (2013)A treatment regimen consisting of HI-6, scopolamine, and physostigmine (termed the physostigmine regimen) has been based on the serendipitous discovery that it exerts powerful antidotal effects against high levels of soman ...