Browsing by Author "Hepnarova, Vendula"

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    • Investigation of new orexin 2 receptor modulators using in silico and in vitro methods 

      Janockova, Jana; Dolezal, Rafael; Nepovimova, Eugenie; Kobrlova, Tereza; Benkova, Marketa; Kuca, Kamil; Konecny, Jan; Mezeiova, Eva; Melikova, Michaela; Hepnarova, Vendula; Ring, Avi; Soukup, Ondrej; Korabecny, Jan (2018)
      The neuropeptides, orexin A and orexin B (also known as hypocretins), are produced in hypothalamic neurons and belong to ligands for orphan G protein-coupled receptors. Generally, the primary role of orexins is to act as ...