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Response of circulating immune cells to major gunshot injury, haemorrhage, and acute surgery
(2005)
Purpose:
The purpose of this study was to use an established porcine model to investigate the effects on immune function of severe gunshot injury.
Methods:
Twelve pigs sustained two standardised rounds, one through ...
Severe gunshot injuries in a porcine model: impact on central markers of innate immunity
(2011)
Background
The mechanisms behind lipopolysaccharide (LPS) tolerance remain obscure. LPS signals through Toll-like receptor 4 (TLR4) and severe trauma/haemorrhage may influence binding and signalling through this receptor, ...